Dexmedetomidine for Controlled Hypotension In Middle Ear Surgery with Low-Flow Anesthesia
نویسندگان
چکیده
middle ear surgery. Dexmedetomidine can be a potential agent in controlled hypotension. In this study we investigated efficacy of dexmedetomidine as an adjunct to induce controlled hypotension in tympanoplasty with low-flow anesthesia. Materials and Methods: Forty patients undergoing middle ear surgery were studied. Anesthesia was induced with thiopental and vecuronium bromide. Maintenance of anesthesia was achieved by 1.5 % isoflurane delivered in mixture of O2 and N2O, 4.4 L.per minute for 10 min and then flow rate was reduced to 1 L.min-1 and isoflurane concentration increased 2 %. Group Dexmedetomidine (In Group D, n=20), Dexmedetomidine (0,1μg.kg-1.min-1 for 10 minutes) was administered before induction and continued with a rate between 0,2-0,7 μg.kg-1.h-1 and Group Saline (Group S, n=20) received normal saline with a rate of 50 ml.h-1. Infusions were stopped with the end of microsurgery. Twenty minutes before the replacement of tympanic membrane greft, N2O was discontinued and then the patients were extubated. Hemodynamic parameters, quality of the surgical field and surgeonʼs satisfaction were evaluated. Results: Demographic and hemodynamic data, the quality of the surgical field and surgeonʼs satisfaction were similar in both groups. Desired level of hypotension was achieved at the 5 th minute in group D, but in group S it couldnʼt be achieved until the 30th minute. Conclusion: Dexmedetomidine was effective in inducing consistent and sustained controlled hypotension in low-flow anesthesia during middle ear microsurgery.
منابع مشابه
Efficacy of dexmedetomidine infusion as an anesthetic adjuvant to provide oligemic surgical field in middle ear surgeries Authors
1 Assistant Professor, Department of Anesthesiology, Govt. Medical College, Srinagar 190010 2 Post Graduate Student, Department of Anesthesiology, Govt. Medical College, Srinagar 190010 3 Sr. Resident, Dept of Pediatrics, Shere Kashmir Institute of Medical Sciences, Soura, Srinagar190011 Corresponding Author Dr Junaida Sarwar Post Graduate Student, Department of Anesthesiology, Govt. Medical, C...
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